Cub Home Opener 2025. On april 4, the cubs will host their home opener at wrigley field against the san diego padres. The chicago cubs will face the los angeles dodgers in tokyo, japan, to start the 2025 season, according to a report by usa today's bob nightengale.

This handy clock will remind you how much time remains before. The houston astros on april 3, 5 and 6.